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Read the announcement: To view or add a comment, sign in BREAKING NEWS: The Food and Drug Administration (FDA) has approved Gazyva (obinutuzumab) for the treatment of adults living with lupus nephritis, supported by positive Phase II and III trial results
Structural optimizations, such as replacing the P2 valine with glycine to form Glutamic acid-Glycine-Citrulline (EGCit) (Figure 7a) or designing a non-linear Exo-EEVCit linker (Figure 7b), have proven effective in resisting neutrophil elastase hydrolysis
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