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The ideal candidate is someone who has a meaningful fat-loss goal, defined as 20 lbs or more to reduce, who is also concerned about how skin quality and connective tissue integrity will hold up through that process

According to the Wegovy Summary of Product Characteristics (SmPC), common adverse reactions include fatigue and headache, which can contribute to feeling generally unwell, particularly during the initial weeks of treatment

They work through the GLP-1 system, but indirectly, and they are far weaker than the injectable agonists

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Tirzepatide Slows Digestion First, tirzepatide delays gastric emptying