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In the multicenter STEP trial with patients with overweight or obesity and heart failure with preserved ejection fraction (STEP-HFpEF), patients treated with semaglutide 2.4 mg had mean percentage reduction in body weight of 13.3% and experienced significant improvements in heart failure-related symptoms, walking distance, and blood pressure measurements from baseline to 52 weeks [15]
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For context, that puts the tablet broadly in the territory of the 2.4 mg weekly injection studied in STEP 1 (Wilding et al., 2021), which is the comparison most patients will reach for
A study to evaluate the safety of exposure to Wegovy during pregnancy
In aggregate, these initial filters removed 80 people (0.29%)
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