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GHK-Cu also stimulates both collagen synthesis and matrix metalloproteinases that break collagen down, so unbalanced or excessive use could in principle disrupt extracellular-matrix homeostasis
Some people notice improvements within a few weeks, while others may require longer depending on the cause and severity of their deficiency
Results vary based on skin tone, sun exposure, and diet, but most users see visible glow in 24 weeks and full brightness in 812 weeks
Deslauriers J, Desmarais C, Sarret P, Grignon S
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