Novo has pinned its hopes on CagriSema to counter Lillys competitive threat
"By identifying which patients are more likely to experience side effects before starting therapy, we can improve tolerability, support long-term adherence, and better match the right treatment to the right patient
Very mild or subclinical hypothyroidism with no significant symptoms In cases of subclinical hypothyroidism, where the TSH is slightly elevated but free T4 remains normal, and the patient has minimal or no symptoms, GLP-1 therapy may be started if there is a strong clinical indication such as prediabetes, elevated waist circumference, or high cardiovascular risk
For these people, the pancreas does not produce enough insulin and/or the body cant properly use the insulin it produces to keep their blood sugar controlled
And for patients who do eventually have surgery, GLP-1s are increasingly part of the picture before and after
The prohibition is sweeping in its scope