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The NHS has experienced significant shortages of diabetes medications due to off-label demand for weight loss, potentially affecting patients who genuinely require these medicines for glycaemic control

doi: 10.1136/gutjnl-2019-319766 100

However, prolonged inflammation can contribute to: Persistent pain Tissue stiffness Muscle inhibition Delayed repair Excess scar formation Reduced mobility Oxidative damage Thymosin beta-4 has demonstrated anti-inflammatory activity in multiple experimental models

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