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The MHRA advises that metformin commonly reduces B12 levels and recommends testing if deficiency is suspected (for example, in patients with anaemia or neuropathy) and considering periodic monitoring in people with risk factors such as higher doses, longer duration of treatment, or other risk factors for deficiency
Preference between them often comes down to whether a patient can tolerate weekly injections or strongly prefers a pill
Our medical team reviews your health history before starting treatment
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Powell WJB et al
Your doctor may discuss adjustment to dosing, or explore other factors that might be causing excessive hunger
2024;261:e230361
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