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Under normal physiologic conditions, intracellular GSH concentrations of neurons are 250- to 500-fold higher than in the CSF, 17 thus limiting the utility of CSF to serve as a biomarker of cellular GSH status
A genetic defect in the biosynthesis of dermatan sulfate proteoglycan: galactosyltransferase I deficiency in fibroblasts from a patient with a progeroid syndrome
[45], systemic injection of melatonin (3 and 10 mg/kg, i.p.) can prevent oxaliplatin-induced cold and mechanical dysalgesia
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ROS Overproduction: The Initiating Driver Hyperglycaemia activates multiple simultaneous ROS sources, including mitochondrial uncoupling, NADPH oxidase isoforms NOX2 and NOX4, and xanthine oxidase upregulation
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