8.3 Atopic dermatitis Treatment of an atopic dermatitis murine model (10 mg/kg) and a human keratinocyte cell line derived from adult human skin (10 M) with formononetin exhibited decreased Thymic Stromal Lymphopoietin (TSLP)/IL-33 levels with increased E-cadherin levels, highlighting its protective effects in allergic diseases [123]
This systemic oxidative stress is thought to contribute to mitochondrial dysfunction, activation of inflammatory pathways, and dysregulation of brain function, potentially explaining symptoms, such as fatigue and cognitive dysfunction (Wood et al., 2021)
Improved Sleep Quality & Circadian Rhythm Regulation Epithalon has been shown to stimulate melatonin production in the pineal gland, which helps regulate sleep-wake cycles
Copper peptides are generally not recommended during pregnancy or breastfeeding due to insufficient research, not known harm
This central action provides a strong basis for its role in neuroprotection against biochemical insults and stress
Sleep and Oxidative Stress: Current Perspectives on the Role of NRF2 Abdul-Rasheed, O.F., et al
