Cathepsin B-mediated activation of trypsinogen in endocytosing macrophages increases severity of pancreatitis in mice
CagriSema data from body composition scans in REDEFINE 1 showed that approximately 67% of total weight loss came from fat mass and 33% from lean soft tissue mass
Depending on how your body reacts, you might want to take Wegovy until you hit your goal weight, and then continue taking it for long-term weight management
Another study in healthy older adults showed supplementation with glyNAC, which increases glutathione levels, led to improvements in strength, gait speed, and body composition (10)
But eating less overall makes it easy to under-eat protein and protein is the one nutrient that protects muscle during weight loss
Regulatory Toxicology and Pharmacology, 117 , 104766