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Passing a bowel movement is painful or takes longer than before
Excess adiposity, particularly visceral fat, is associated with metabolic dysfunction that may affect hormone regulation
The pH and osmolality of the solution may also contribute to transient discomfort or visible skin changes following injection
The main outcomes were major adverse cardiovascular events (MACE), hospitalization for heart failure (HHF) or cardiovascular death
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the combination therapy was significantly associated with a higher percent TBWL in responders and non-responders than GLP-1 analog monotherapy alone
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