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With purpose-build scoring systems being debunked as useful, and mixed diagnostic criteria being used in case studies, this makes potential novel interventions difficult to study
L-carnitine used to treat hyper-ammonia in children with urea-cycle enzyme deficiencies26 and valproate-induced hyper-ammonia.27 The protec tive effects of L-carnitine are centrally mediated by activation of metabotropic Glu receptors at the level of brain ammonia uptake and/or mitochondrial energy metabolism
10.1210/en.2014-1675 56 HolscherC
Always consult with your healthcare provider before relying on supplements for clinical support
B.CacicedoJ
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