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Constipation is managed with adequate fiber, hydration, and if needed, gentle fiber supplements
Xian, H
While they can offer antioxidant support and brighten surface-level pigmentation, their effects are limited compared to oral or injectable forms, as glutathione molecules struggle to penetrate deeply into skin layers
16 This mechanism has been further strengthened by in vivo evidence from murine bilateral renal ischemia-reperfusion injury models, in which vesicles released from injured tubules have been shown to carry the long non-coding RNA WAC-AS1 and suppress antioxidant defenses in neighboring tubular cells
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doi: 10.1186/s12974-022-02570-3 152
