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Dipeptidyl peptidase-4 inhibitors: anti-diabetic drugs with potential effects on cancer
Preclinical studies demonstrate their capacity to reduce retinal ganglion cell apoptosis in diabetic models (Wang et al., 2023)
Frankly, completely false, and others have some merit and are starting to gain some data within the standard scientific community
Specifically, in Burkitt lymphoma, HIF-1 increases PDK mRNA levels, downregulates OXPHOS, 706 and induces a reduction in COX4-1 protein levels, thereby decreasing mitochondrial stability
Stone BM et al
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