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So far, weve put the spotlight on Wegovy and Saxenda, but other GLP-1s are FDA-approved for type 2 diabetes but are also used off-label for the treatment of overweight and obesity

This action on fat metabolism may contribute to weight loss beyond the effects of appetite suppression alone and may also underlie some of the improvements seen in lipid profiles and conditions like MASH

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But skin reactions are common: contact dermatitis, adhesive irritation, redness, and occasional blistering

Hematological testing also revealed no significant toxic effects on red blood cells, white blood cells, or platelet counts (Figs