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Last Updated: September 2025

The decision to add B12 is made by individual prescribers working with compounding pharmacies, which is why B12 only appears in compounded formulations

If using a 5/8-inch needle on the thigh, always inject at 45 degrees unless you have substantial subcutaneous fat

Here are some groups of people who might benefit from B12 supplementation: Vegetarians and Vegans: Since B12 is primarily found in animal products, those who avoid meat, dairy, and eggs may be at risk of deficiency

This isn't just guesswork