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They found that NrCAM is expressed in cortical astrocytes and is necessary to restrict neuronal infiltration through astrocytic processes

The NNMT enzyme it inhibits is constitutively expressed in adipose tissue and liver, meaning timing relative to meals is less critical than consistency

Oxidative stress also seems to be an important pathophysiological mechanism of NAFLD (190)

For comparison, transdermal medications that work well (like nicotine patches) involve molecules smaller than 500 daltons

Porto Cervo, Italy

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