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Its activity is dynamically modulated by phosphorylation and dephosphorylation, primarily mediated by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), respectively

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It was also reported that using oral treatment did not result in any new neurological complications

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The prepared inhibitor solutions (in 1% DMSO) were added to the embryo medium from 9 to 57 hpf (hours post fertilization, total 48 h exposure)