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To rule out the possibility that lean mass loss following BW reduction could have affected creatinine-based eGFR measurement, the muscle mass-independent endogenous filtration marker cystatin C was used to confirm the renal favorable effects attributed to tirzepatide [52]

2.3.2 Changes Brought by Acetylation: Stability and Membrane Permeability The acetyl group acts like a molecular protective shield, completely shielding the thiol group during transportation

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