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The pathophysiology of DGP is postulated to involve hyperglycemia or extreme hypoglycemia-induced impairment of gastrointestinal (GI) vagal dysfunction from the loss of Cajals interstitial cells and enteric glial cells
In the early 1990s, scientists observed that there was a toxin found in Gila monster saliva which caused its prey to develop low blood sugars (hypoglycemia), making them an easy, tasty treat
[7] The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a Drug Safety Update recommending periodic B12 monitoring in patients on long-term metformin therapy
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