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Rapid weight loss has been associated with gallbladder-related disorders including cholelithiasis and cholecystitis [67, 68], and these adverse events, while rare, have been observed more with GLP-1RAs compared with placebo in clinical trials [21, 38]
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Ethics approval and consent to participate This study was reviewed by the Natural and Non-prescription Health Products Directorate (NNHPD), Health Canada and a research ethics board, which granted ethics approval in December, 2014
doi: 10.21037/tau.2019.11.30
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