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Animal offspring exposed to spironolactone during late pregnancy exhibited changes in the reproductive tract, including dose-dependent decreases in weights of the ventral prostate and seminal vesicle in males, ovaries and uteri that were enlarged in females, and other indications of endocrine dysfunction that persisted into adulthood
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Glossary GLP-1 (Glucagon-Like Peptide-1) An incretin hormone produced in the gut that suppresses appetite, slows gastric emptying, and promotes insulin secretion
Therapeutic Applications of Hydrogels in Oral Drug Delivery
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