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However individuals with certain medical conditions, pregnancy, or known allergies should always consult a qualified medical professional before starting treatment
Complementing these direct effects, luteolin activates the Nrf2/ARE antioxidant pathway by promoting dissociation of Nrf2 from Keap1, facilitating its nuclear translocation and induction of antioxidant genes including HO-1, NQO1, SOD, and CAT (Thiruvengadam et al., 2021)
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Frequent loss of heterozygosity (LOH) on chromosome 3p in lung tumors was associated with low GPx1 enzyme activities, which may affect the prognosis of lung cancer patients [86]
This risk does not apply to oral or injection forms at standard doses
PMID:35955857
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