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This anhedonia typically resolves over time but may require months or years depending on the severity and duration of substance use
Spine 38 , E1533E1540 (2013)
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As we age, stomach acid production can decline (atrophic gastritis), which makes it harder to extract B12 from food or pills
The trial had a 26-week treatment period, including a 6-week dose-escalation period, and a 6-week follow-up period without treatment
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