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Undeniably, Ca 2+ fluxes are crucial for almost all reported RCD pathways in erythrocytes, whereas in apoptosis, Ca 2+ elevation mediates primarily the mitochondrial outer membrane permeabilization (MOMP), triggering the intrinsic apoptosis [192]

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In asthma patients, lower levels of SOD, CAT (73) and GPx (74) activity were observed in BAL fluids and respiratory epithelial cells

We typically start with a lower dosage and increase it gradually to minimize potential side effects