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6.6 kcal/mol) through the following three polar contacts: asparagine (Asn)194, Arg-107, and aspartic acid (Asp)189

E, F, subungual haematoma with homogenous reddish brown to black colour Differential diagnoses could include: melanocytic lesions naevi (moles) lentigo (increased single melanocytes) melanoma in situ melanoma subungal squamous cell carcinoma (SCC) subungual haemorrhage fungal infection systemic illness (including systemic lupus erythematosus, scleroderma) drug-induced pigmentation ethnic-type pigmentation (can often involve multiple digits)

Diabetic Retinopathy Patients with diabetic eye disease should proceed with caution and consult their healthcare provider before considering Semaglutide or Tirzepatide

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Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were calculated for all predictors

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