Scientific References (External Links) Nature Chemical Biology: Small molecule inhibitors of nicotinamide N-methyltransferase View Study Biochemical Pharmacology: Nicotinamide N-methyltransferase: A promising target for treating metabolic disorders View Study FASEB Journal: Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity in mice View Study Journal of Biological Chemistry: Inhibition of nicotinamide N-methyltransferase in vivo regulates cellular energy metabolism View Study
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The brain has high demands of nutrients and energy, despite the fact that the BBB places a significant amount of restrictions on the movement of substances across it, because of this, the brain is able to absorb endogenous chemicals through a variety of both passive and active transport pathways (Figure 2)
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Fadilah NIM, Maarof M, Motta A, Tabata Y, Fauzi MB
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