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PALI-2108 uses a galactose-based prodrug system that remains minimally absorbed until it reaches the colon, where bacterial enzymes activate the compound to limit systemic exposure and target local inflammation
Most symptoms improve within 4-8 weeks as the body adjusts to therapy
In humans, its established as a selective GH secretagogue 9 with minimal off-target hormone effects even at doses far above the effective GH dose
Eze, C.N
Based on glycemic response and tolerability, the dose may be increased to 1 mg or 2 mg weekly
Medications distribute differently across these compartments, and the rate of distribution affects the concentration curve
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