Topical Copper Peptides Affects surface layers of skin only Limited penetration through skin barrier Localized effect only where applied Good for maintenance, not transformation No systemic anti-aging benefit Available over-the-counter Injectable GHK-Cu Full systemic delivery to all tissues Reaches dermis, follicles, and healing sites Whole-body anti-aging effect More potent collagen stimulation Gene expression modulation (4,000+ genes) Requires medical prescription They are not mutually exclusive
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An ex vivo experimental model after exposure to UV A and B, infrared-A radiations and visible light on human skin fragments which was obtained from elective plastic surgery, when pycnogenol was applied on the skin
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It is, however, the scientific basis for taking these compounds seriously as a research area rather than dismissing them on grounds of limited human data alone
The results in humans, however, were modest enough that it has not advanced to Phase 3 approval for any fat loss indication
