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It is a peptide made up of three amino acids: Glutamic acid, Cysteine and Glycine

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Footnote Nonstandard Abbreviations and Acronyms AMPLITUDE-O Effect of Efpeglenatide on Cardiovascular Outcomes CANVAS Canagliflozin Cardiovascular Assessment CKD chronic kidney disease CREDENCE Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation eGFR estimated glomerular filtration rate ELIXA Evaluation of Lixisenatide in Acute Coronary Syndrome EXSCEL Exenatide Study of Cardiovascular Event Lowering FIDELIO-DKD Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease FIGARO-DKD Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease GLP-1 RA glucagon-like peptide-1 receptor agonists Harmony Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus LEADER Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results MACE major adverse cardiovascular events ns-MRA nonsteroidal mineralocorticoid receptor antagonist PIONEER-6 A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes REWIND Dulaglutide and Cardiovascular Outcomes in Type 2 Diabetes SGLT2i sodium glucose cotransporter 2 inhibitor SUSTAIN-6 Trial to Evaluate Cardiovascular and Other Long-Term Outcomes With Semaglutide in Subjects With Type 2 Diabetes UACR urine albumin:creatinine ratio Supplemental Material File (10.1161.circulationaha.123.067584 supplement.pdf) Download 666.82 KB File (circ_circulationaha-2023-067584_supp1.pdf) Download 666.82 KB REFERENCES 1

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