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Hales CM, Carroll MD, Fryar CD, Ogden CL (2020) Prevalence of obesity and severe obesity among adults: United States, 20172018

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Each of these mutations likely destabilise the PfK13 protein, as resistant clinical isolates and laboratory parasites carrying the resistance-associated PfK13 mutations R539T, C580Y, R561H and M579I contain reduced cellular levels of PfK13 612

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