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Whether those acute effects translate to sustained synaptogenic benefits over weeks or months remains an open questionhuman trial data on Dihexa is limited to a handful of small-scale studies, none of which directly compared oral vs sublingual pharmacokinetics in humans

Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial

An additional 202 articles were excluded for the following reasons: irrelevant study population (n=60), unrelated interventions (n=90), insufficient or incomplete data (n=52), and language limitations (non-English)

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Data analysis was predetermined and performed blind to expected outcomes

Both forms can be highly effectivebut they tend to excel in different therapeutic contexts