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Here, we found that the neuronal conditional-knockout (KO) of glutamyl-cysteine-ligase catalytic-subunit (GCLC), a rate-limiting enzyme for glutathione synthesis, induced brain atrophy accompanied by neuronal loss and neuroinflammation

Neuroprotective Effects: Emerging evidence suggests that semaglutide may have neuroprotective effects, potentially benefiting individuals with neurodegenerative diseases such as Alzheimers and Parkinsons

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Briefly, PWA mice were individually placed in the metabolic cages 24 h prior to initiation of the experiment to allow for an adaptation period

Diarrhea affected 9% of the oral semaglutide group 2

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