Overall, the therapeutic efficacy of tirzepatide in obesity management and diabetes care is evident, making it a valuable option for those looking to lose weight and maintain their health
doi:10.1056/NEJMoa2206038 Bellini A, Keegan THM, Li Q, et al
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Short-acting formulations reach peak plasma concentrations within 1-3.5 hours and have shorter elimination half-lives, while long-acting agents like semaglutide have half-lives of approximately one week, allowing for sustained therapeutic effects
We found that tirzepatide is superior in reducing HbA 1c compared with other injectable therapies, in particular basal insulin and once-weekly GLP-1 RAs