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Glycemic Control: Investigations include changes in fasting glucose, post-prandial responses, and HbA1c in metabolic-disease cohorts

Trial averages: 20.2% on tirzepatide and 13.7% on semaglutide at 72 weeks (SURMOUNT-5)

It is worth noting, they say, given their cardiovascular history, that SELECT patients were already on other cardio-protective medications, for example, to tackle cholesterol and blood pressure, meaning semaglutide had benefits on top of these other agents

(2025, May 29)

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Patients should be counseled that fiber without sufficient hydration can paradoxically worsen constipation