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Among the various glucose-lowering agents used to treat T2D, 2 classes of incretin-based therapies, glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RA) and dipeptidyl peptidase-4 (DPP-4) inhibitors (DPP4i), lower postprandial TGs (5, 6)

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Tirzepatide, which combines GIP and GLP-1 activity, demonstrated approximately 40% greater weight loss than GLP-1 alone, validating the synergistic relationship between these receptors

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These data confirm that using ascorbic acid alone leads to greater oxidation and that it must, therefore, be used in the presence of SO 2 [5, 57]

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