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GLP-1 receptor agonists have a very good profile in terms of reducing excess weight and inflammation, both of which have established links to cancer," Jiang Bian, PhD, MS, FACMI, associate dean for data science at Indiana University School of Medicine and chief data scientist for IU Health and Regenstrief Institute, told Healio
Clinical trials comparing 7.2mg to the standard 2.4mg dose showed greater weight loss results, with patients on the higher dose achieving an average of 20.7% weight loss compared to 17.5% on 2.4mg over 72 weeks
Discontinuing the medicine necessitates a thoughtful plan with a healthcare professional, but current research supports the notion that continual therapy is required for long-term results
A large observational study or registry would be needed to fully rule it out, but given how uncommon MTC is (1 in 50k maybe) and how many have now taken GLP-1 RAs (millions), likely any major signal would have emerged by now
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