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Ordinal scales, such as ALSFRS-R, where total sum scores are compared within participants, sometimes under- or over-value changes (i.e., the difference in scores in patients who go from walking up stairs to using a handrail is considered equivalent to the difference between feeding oneself and relying on others for all feeds)

WADA-prohibited at all times for in-competition and out-of-competition athletes

For example, peptides like Selank and Semax have been researched for their potential effects on mood, focus, and cognitive performance

Int J Mol Sci 23:4075

doi: 10.1007/S11882-012-0296-X 203 Briceno NoriegaDZenkerHECroesCAEwazARuinemans-KoertsJSavelkoulHFJet al

The peptide glycyl-L-histidyl-L-lysine is an endogenous antioxidant in living organisms, possibly by diminishing hydroxyl and peroxyl radicals