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Semaglutide might indirectly support testosterone production by improving metabolic health, but more research is needed, especially in women, to fully understand the connection
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[2] Human clinical trials in humans have been more limited
Semaglutide and tirzepatide do not activate it
PLA Med
Abbreviations AIWG: Antipsychotic-induced weight gain AP(s): Antipsychotic(s) BMI: Body mass index BPRS: Brief Psychiatric Rating Scale CI: Confidence interval DM2: Diabetes mellitus type 2 ESM: Experience sampling method GLP-1: Glucagon-like peptide-1 HbA1c: Glycated haemoglobin HDL: High-density lipoprotein IRB: Institutional review board KQOL: Kemp Quality of Life scale LDL: Low-density lipoprotein MOSA: Management of Obesity with Semaglutide in AIWG NMA: Network meta-analysis QoL: Quality of life SMI: Severe mental illness UKU-SERS: UKU-Side Effect Rating Scale References van Alphen C, Ammeraal M, Blanke C, Boonstra N, Boumans H, Bruggeman R, et al
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