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Most importantly, design studies to answer mechanistic questions (does the peptide activate the expected pathway?) before efficacy questions (does it improve venous function?)

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A complete kit includes: A sealed vial or glass ampoule of B12 (cyanocobalamin or methylcobalamin) A 3 mL syringe A drawing needle (typically 18-21 gauge) An injecting needle: 22-25 gauge, 1 to 1.5 inch for intramuscular (IM)

How to inject b12 will depend on which you choose

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