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On the other hand, it is also clear that prolonged LC supplementation elevates fasting plasma TMAO [16,17,18, 58, 59], compound supposed to be pro-atherogenic [61]

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Once obtained, H 2 O 2 can be degraded in mitochondria via the GSH redox system, employing glutathione peroxidases (Gpxs) and GRs, but also through peroxiredoxins (Prxs), a family of thiol-specific peroxidases

The weight loss observed in diabetic subjects led to investigate the potential use of this molecule as anti-obesity drug