In lab and clinical research, its been observed to activate fibroblasts (the cells that produce collagen), increase glycosaminoglycan synthesis (which helps skin retain water), modulate matrix metalloproteinases (MMPs, the enzymes that break down old tissue), and act as a copper cofactor in antioxidant pathways
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When taken together, these findings highlight the need for caution in assuming that every compound that is produced by the body is good
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Neuropsychopharmacology 37:338349 Garzn J, Rodrguez-Muoz M, Snchez-Blzquez P (2012) Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance