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The Bottom Line Erectile dysfunction is common, but it is not just part of ageing. It often reflects broader health issues, especially obesity and cardiovascular disease

For regulatory risk-to-effect ratio, peptide secretagogues like CJC-1295/ipamorelin have a lower legal and health risk profile, though they also have less effect magnitude

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Serious adverse events are rare but include allergic reactions to formulation excipients (benzyl alcohol, methylparaben) and, in patients with renal impairment, carnitine accumulation leading to fishy body odour

doi:10.3390/genes12071093