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First: the lipolytic effect in animal models (in rats and mice on a high-fat diet) did not translate to humans with stabilized obesity

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The authors cited the scientific foundation provided by these studies as supporting ongoing and projected clinical trials in dermal wound repair, corneal injuries, and cardiac and CNS tissue regeneration

Theoretical Risks and Safety Nuance Preclinical Safety Observations While no major adverse events are reported in the limited human data, researchers note theoretical concerns based on animal models