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PMID: 33468060

So it was hypothesized there were some suite of mechanisms by which your gut actually signaled the rest of your body that you had eaten something

Naturally produced in the liver, this powerful tripeptide is made up of glutamine, cysteine, and glycine, and plays a vital role in defending your cells from oxidative stress, environmental toxins, and inflammation

Since it has multiple elimination pathways, i.e., renal and metabolic degradation, it has been found to present similar systemic exposure pre- and post-surgery, independent of the type of procedure [42]

doi: 10.1097/HCO.0b013e3281532b53 79 SowersJR

Research suggests fixed doses provide adequate tissue exposure regardless of body size within normal ranges