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Compared to the placebo (-4.0), liraglutide resulted in a greater change in BMI as a percentage of the 95th percentile (-14.0), and an estimated treatment difference of 10.0 (95% CI, 15.1 to 4.8) was observed
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The most frequent ( 10% incidence in any treatment group) TEAEs were thrombocytopenia (4% of episodes with carglumic acid + ammonia scavengers vs 5% with carglumic acid alone and 21% with ammonia scavengers alone), hyperglycaemia (4 vs 3 and 15%), hypokalaemia (0 vs 3 and 18%), coagulopathy (0 vs 3 and 15%), hypocalcaemia (0 vs 3 and 12%) and respiratory distress (0 vs 0 and 12%)
FEBS Lett 86:8991 Anderson ME, Meister A (1980) Dynamic state of glutathione in blood plasma
Brahimaj 2017)
Vanneman M, Dranoff G (2012) Combining immunotherapy and targeted therapies in cancer treatment
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