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However, given the large sample size of over 6,000 participants and balancing of factors such as age, sex, etc., these results do provide a valid divergence from other studies, and require more research in future studies

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Daily oral orforglipron, a nonpeptide GLP-1 receptor agonist, was associated with weight reduction [30] [31], offering potential advantages regarding administration route and patient convenience

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Spring 2026 is an ideal time to consult, as patients who began GLP-1 medications in late 2025 are now approaching stable weights and can plan body contouring with sufficient recovery time before summer

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