Side effect tolerance plays a role
Persistent vomiting and nausea can lead to dehydration, electrolyte imbalances, and metabolic disturbances that may manifest as dyspnea
How Genetics Influence Fibroid Growth A 2015 study looked into genomic features that distinguish metabolic subtypes of fibroids, and discovered that genetic expression of insulin-like growth factor, prolactin, and Wnt/-catenin proteins (involved in normal as well as abnormal cell proliferation) may characterize fibroids with different response patterns
Inositol for the prevention of gestational diabetes: a systematic review and meta-analysis of randomized controlled trials
Average weight loss hides how many people actually hit meaningful thresholds, so the trials also report the share of participants reaching 5%, 10%, 15%, and 20% body-weight reductions
GI effects are common