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The enhanced hepatic mitochondrial activity in the context of TKT deficiency has been shown to be the result of increased phospholipid synthesis, particularly increased synthesis of phosphatidylcholine which represents the major phospholipid in the mitochondrial membrane

Key Takeaway: Topical application alone faces bioavailability limitations

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When compounded professionally, it is well tolerated for daily topical use

It is a synthetic pentadecapeptide (15 amino acids) that is a fragment of a protective protein from gastric juice