Transgenic expression of FGF21 in pancreatic acini reduces tissue damage, lipid accumulation, and fibrosis induced by cerulein, all of which were exacerbated in animals lacking FGF21 (221, 266)
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Research has focused on its role in stimulating eumelanin production, with additional studies examining its effects on energy homeostasis
Patients should be aware of both common and serious side effects before starting treatment
Semaglutide should be avoided during pregnancy and breast-feeding, and should be discontinued at least 2 months before a planned pregnancy
Regular monitoring and follow-up with a healthcare provider are essential